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Merck

GP6

glycoprotein VI (platelet)

Synonyms:
BDPLT11, GPIV, GPVI
Species:
Human GP6 (51206), Mouse Gp6 (243816), Rat Gp6 (684555), dog GP6 (484303), cow GP6 (100336616), domestic cat GP6 (101093562), sheep GP6 (101123066)
UniProtKB ID:
Q9HCN6, Q9HCN7, Q9UIF2
Gene ID:
  • Human(51206) Summary: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  • Mouse(243816) glycoprotein 6 (platelet)
  • Rat(684555) glycoprotein 6 (platelet)
  • dog(484303) glycoprotein VI (platelet)
  • cow(100336616) glycoprotein VI (platelet)
  • domestic cat(101093562) glycoprotein VI (platelet)
  • sheep(101123066) glycoprotein VI (platelet)

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ELISA

Product Number
Description
Species
RAB1495
Human GPVI ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
ABS446
Anti-GPVI Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry
western blot
MABT418
Anti-GPVI Antibody, clone 8A2, Detection Antibody, clone 8A2, from rat,
Species Reactivity
human
Application
ELISA
western blot
SAB2100952
Anti-GP6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
PRS4769
Anti-GPVI (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
PRS4771
Anti-GPVI (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
EHU076911
MISSION® esiRNA, targeting human GP6,
Species
human