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Merck

GGCT

gamma-glutamylcyclotransferase

Synonyms:
C7orf24, CRF21, GCTG, GGC
Species:
UniProtKB ID:
Gene ID:
  • Human(79017) Summary: The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(110175) gamma-glutamyl cyclotransferase
  • Rat(362368) gamma-glutamyl cyclotransferase
  • chicken(420676) gamma-glutamylcyclotransferase
  • dog(611603) gamma-glutamylcyclotransferase
  • domestic cat(101087219) gamma-glutamylcyclotransferase
  • cow(533374) gamma-glutamylcyclotransferase
  • sheep(101102474) gamma-glutamylcyclotransferase
  • domestic guinea pig(100723170) gamma-glutamylcyclotransferase
  • naked mole-rat(101723887) gamma-glutamylcyclotransferase

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GGCT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-GGCT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ggct,
Species
mouse
MISSION® esiRNA, targeting human GGCT,
Species
human