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GFRA2

GDNF family receptor alpha 2

Synonyms:
GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2
Species:
UniProtKB ID:
Gene ID:
  • Human(2675) Summary: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(14586) glial cell line derived neurotrophic factor family receptor alpha 2
  • Rat(25136) GDNF family receptor alpha 2
  • chicken(395993) GDNF family receptor alpha 2
  • cow(514036) GDNF family receptor alpha 2
  • Horse(100146260) GDNF family receptor alpha 2
  • domestic cat(101091865) GDNF family receptor alpha 2
  • dog(609172) GDNF family receptor alpha 2
  • domestic guinea pig(100727079) GDNF family receptor alpha 2
  • naked mole-rat(101706123) GDNF family receptor alpha 2
  • sheep(101119877) GDNF family receptor alpha 2

Custom & Knockdown Gene Products

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  • Custom Gene Products

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ELISA

Product Number
Description
Species
Human GFR alpha-2 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GFRA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-GFRA2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, mouse, pig, rabbit, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gfra2,
Species
mouse
MISSION® esiRNA, targeting human GFRA2,
Species
human