GCDH
glutaryl-CoA dehydrogenase
Synonyms:
ACAD5, GCD
Species:
Human GCDH (2639), Mouse Gcdh (270076), Rat Gcdh (364975), Zebrafish gcdh (393860), cow GCDH (506310), Horse GCDH (100063310), domestic cat GCDH (101086880), chicken GCDH (771098), dog GCDH (476696), sheep GCDH (101122190) ...More
UniProtKB ID:
Gene ID:
- Human(2639) Summary: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
- Mouse(270076) glutaryl-Coenzyme A dehydrogenase
- Rat(364975) glutaryl-CoA dehydrogenase
- Zebrafish(393860) glutaryl-Coenzyme A dehydrogenase
- cow(506310) glutaryl-CoA dehydrogenase
- Horse(100063310) glutaryl-CoA dehydrogenase
- domestic cat(101086880) glutaryl-CoA dehydrogenase
- chicken(771098) glutaryl-CoA dehydrogenase
- dog(476696) glutaryl-CoA dehydrogenase
- sheep(101122190) glutaryl-CoA dehydrogenase
- Domestic Rabbit(100343376) glutaryl-CoA dehydrogenase
- naked mole-rat(101718348) glutaryl-CoA dehydrogenase
- domestic guinea pig(100714939) glutaryl-CoA dehydrogenase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GCDH antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-GCDH antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rabbit, rat
Application
western blot
Anti-GCDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GCDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot