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GADD45B

growth arrest and DNA-damage-inducible, beta

Synonyms:
GADD45BETA, MYD118
Species:
UniProtKB ID:
Gene ID:
  • Human(4616) Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]
  • Mouse(17873) growth arrest and DNA-damage-inducible 45 beta
  • Rat(299626) growth arrest and DNA-damage-inducible, beta
  • chicken(429929) growth arrest and DNA-damage-inducible, beta
  • domestic cat(101087971) growth arrest and DNA-damage-inducible, beta
  • cow(618405) growth arrest and DNA-damage-inducible, beta
  • dog(485069) growth arrest and DNA-damage-inducible, beta
  • sheep(101120573) growth arrest and DNA-damage-inducible, beta
  • naked mole-rat(101710909) growth arrest and DNA-damage-inducible, beta
  • domestic guinea pig(100730773) growth arrest and DNA-damage-inducible, beta

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GADD45B, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rat
Application
immunohistochemistry
western blot
Anti-GADD45B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GADD45B,
Species
human
MISSION® esiRNA, targeting mouse Gadd45b,
Species
mouse