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GAB2

GRB2-associated binding protein 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(9846) Summary: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
  • Mouse(14389) growth factor receptor bound protein 2-associated protein 2
  • Rat(84477) GRB2-associated binding protein 2
  • sheep(101115743) GRB2-associated binding protein 2
  • Domestic Rabbit(100349301) GRB2-associated binding protein 2
  • domestic guinea pig(100732375) GRB2-associated binding protein 2
  • naked mole-rat(101719954) GRB2-associated binding protein 2
  • Zebrafish(564517) GRB2-associated binding protein 2
  • cow(529346) GRB2-associated binding protein 2
  • Horse(100062877) GRB2-associated binding protein 2
  • domestic cat(101101410) GRB2-associated binding protein 2
  • dog(485167) GRB2-associated binding protein 2
  • chicken(419027) GRB2-associated binding protein 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-GAB2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-GAB2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-GAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-phospho-GRB2 (pSer159) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse GAB2,
Species
mouse
MISSION® esiRNA, targeting human GAB2,
Species
human