FZD6
frizzled family receptor 6
Synonyms:
FZ-6, FZ6, HFZ6, NDNC10
Species:
Human FZD6 (8323), Mouse Fzd6 (14368), Rat Fzd6 (282581), Zebrafish fzd6 (393533), cow FZD6 (445418), dog FZD6 (403610), domestic cat FZD6 (101101443), chicken FZD6 (378788), naked mole-rat Fzd6 (101722552), domestic guinea pig Fzd6 (100719748)
UniProtKB ID:
Gene ID:
- Human(8323) Summary: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]
- Mouse(14368) frizzled homolog 6 (Drosophila)
- Rat(282581) frizzled family receptor 6
- Zebrafish(393533) frizzled homolog 6 (Drosophila)
- cow(445418) frizzled family receptor 6
- dog(403610) frizzled family receptor 6
- domestic cat(101101443) frizzled family receptor 6
- chicken(378788) frizzled family receptor 6
- naked mole-rat(101722552) frizzled family receptor 6
- domestic guinea pig(100719748) frizzled family receptor 6
- sheep(101122197) frizzled family receptor 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-FZD6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunofluorescence
Anti-FZD6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-FZD6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry