FPGT
fucose-1-phosphate guanylyltransferase
Synonyms:
GFPP
Species:
Human FPGT (8790), Mouse Fpgt (75540), Rat Fpgt (310935), domestic guinea pig Fpgt (100718633), Domestic Rabbit FPGT (100533991), Zebrafish fpgt (553792), dog FPGT (100533995), cow FPGT (100138313), Horse FPGT (100533993), domestic cat FPGT (101085816)
UniProtKB ID:
Gene ID:
- Human(8790) Summary: L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene. [provided by RefSeq, Dec 2010]
- Mouse(75540) fucose-1-phosphate guanylyltransferase
- Rat(310935) fucose-1-phosphate guanylyltransferase
- domestic guinea pig(100718633) fucose-1-phosphate guanylyltransferase
- Domestic Rabbit(100533991) fucose-1-phosphate guanylyltransferase
- Zebrafish(553792) fucose-1-phosphate guanylyltransferase
- dog(100533995) fucose-1-phosphate guanylyltransferase
- cow(100138313) fucose-1-phosphate guanylyltransferase
- Horse(100533993) fucose-1-phosphate guanylyltransferase
- domestic cat(101085816) fucose-1-phosphate guanylyltransferase
- chicken(100533998) fucose-1-phosphate guanylyltransferase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-FPGT antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-FPGT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot