FMO2
flavin containing monooxygenase 2 (non-functional)
Synonyms:
FMO 1B1, FMO 2, FMO1B1
Species:
Human FMO2 (2327), Mouse Fmo2 (55990), Rat Fmo2 (246245), domestic guinea pig Fmo2 (100725320), domestic guinea pig Fmo2 (100135520), naked mole-rat Fmo2 (101710590), sheep FMO2 (101104842), domestic cat FMO2 (101086867), cow FMO2 (504401), dog FMO2 (480076)
UniProtKB ID:
Gene ID:
- Human(2327) Summary: The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in some human populations, this enzyme is truncated and likely degraded rapidly. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1. [provided by RefSeq, Jun 2013]
- Mouse(55990) flavin containing monooxygenase 2
- Rat(246245) flavin containing monooxygenase 2
- domestic guinea pig(100725320) flavin containing monooxygenase 2 (non-functional)
- domestic guinea pig(100135520) flavin containing monooxygenase 2
- naked mole-rat(101710590) flavin containing monooxygenase 2 (non-functional)
- sheep(101104842) flavin containing monooxygenase 2 (non-functional)
- domestic cat(101086867) flavin containing monooxygenase 2 (non-functional)
- cow(504401) flavin containing monooxygenase 2 (non-functional)
- dog(480076) flavin containing monooxygenase 2 (non-functional)
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