FGD1
FYVE, RhoGEF and PH domain containing 1
Synonyms:
AAS, FGDY, MRXS16, ZFYVE3
Species:
Human FGD1 (2245), Mouse Fgd1 (14163), Rat Fgd1 (363460), Zebrafish fgd1 (560305), dog FGD1 (491901), domestic cat FGD1 (101094403), cow FGD1 (100124501), sheep FGD1 (101117050), domestic guinea pig Fgd1 (100718541), naked mole-rat Fgd1 (101720101)
UniProtKB ID:
Gene ID:
- Human(2245) Summary: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011]
- Mouse(14163) FYVE, RhoGEF and PH domain containing 1
- Rat(363460) FYVE, RhoGEF and PH domain containing 1
- Zebrafish(560305) FYVE, RhoGEF and PH domain containing 1
- dog(491901) FYVE, RhoGEF and PH domain containing 1
- domestic cat(101094403) FYVE, RhoGEF and PH domain containing 1
- cow(100124501) FYVE, RhoGEF and PH domain containing 1
- sheep(101117050) FYVE, RhoGEF and PH domain containing 1
- domestic guinea pig(100718541) FYVE, RhoGEF and PH domain containing 1
- naked mole-rat(101720101) FYVE, RhoGEF and PH domain containing 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Fgd1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-FGD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Anti-FGD1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot