FCN3
ficolin (collagen/fibrinogen domain containing) 3
Synonyms:
FCNH, HAKA1
Species:
Human FCN3 (8547), dog FCN3 (100685339), Horse FCN3 (100070924), cow FCN3 (782648), domestic cat FCN3 (101082073), domestic guinea pig Fcn3 (100736025), naked mole-rat Fcn3 (101698364), sheep FCN3 (101113473)
UniProtKB ID:
Gene ID:
- Human(8547) Summary: Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq, Jul 2008]
- dog(100685339) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
- Horse(100070924) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
- cow(782648) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
- domestic cat(101082073) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
- domestic guinea pig(100736025) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
- naked mole-rat(101698364) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
- sheep(101113473) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-FCN3 antibody produced in mouse, clone 4B4, ascites fluid,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
esiRNA
Product Number
Description
Species