FBXO32
F-box protein 32
Sinónimos:
Fbx32, MAFbx
Especie:
Human FBXO32 (114907), Mouse Fbxo32 (67731), Rat Fbxo32 (171043), naked mole-rat Fbxo32 (101718496), domestic guinea pig Fbxo32 (100726187), sheep FBXO32 (100142676), Domestic Rabbit FBXO32 (100356177), Zebrafish fbxo32 (393891), chicken FBXO32 (420343), dog FBXO32 (475091) ...Más
ID UniProtKB:
ID del gen:
- Human(114907) Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
- Mouse(67731) F-box protein 32
- Rat(171043) F-box protein 32
- naked mole-rat(101718496) F-box protein 32
- domestic guinea pig(100726187) F-box protein 32
- sheep(100142676) F-box protein 32
- Domestic Rabbit(100356177) F-box protein 32
- Zebrafish(393891) F-box protein 32
- chicken(420343) F-box protein 32
- dog(475091) F-box protein 32
- Horse(100057506) F-box protein 32
- cow(513776) F-box protein 32
- domestic cat(101083398) F-box protein 32
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Fbx32/FBOX32 antibody produced in rabbit, ,
Reactividad de especies
mouse, rat
Aplicación
immunohistochemistry
western blot
western blot