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Merck

F11R

F11 receptor

Synonyms:
CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
Species:
UniProtKB ID:
Gene ID:
  • Human(50848) Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
  • Mouse(16456) F11 receptor
  • Rat(116479) F11 receptor
  • Zebrafish(323696) F11 receptor
  • dog(478974) F11 receptor
  • cow(281258) F11 receptor
  • domestic cat(653015) F11 receptor
  • chicken(100036512) F11 receptor
  • sheep(780487) F11 receptor
  • naked mole-rat(101713536) F11 receptor
  • domestic guinea pig(100733207) F11 receptor

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Mouse F11r / Junctional Adhesion Molecule A ELISA Kit, ,
Species
mouse
Rat JAM-A ELISA, for serum, plasma and cell culture supernatants,
Species
rat
Human JAM-A ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-F11R antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-F11R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-F11R antibody produced in mouse, clone 2E3-1C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

proximity ligation assay

western blot
Anti-JAM-A Antibody, clone 2E9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunohistochemistry

western blot
Anti-JAM1 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM275, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human F11R,
Species
human
MISSION® esiRNA, targeting mouse F11r,
Species
mouse