ERCC2
excision repair cross-complementing rodent repair deficiency, complementation group 2
Synonyms:
COFS2, EM9, TTD, XPD
Species:
Human ERCC2 (2068), Mouse Ercc2 (13871), Rat Ercc2 (308415), domestic guinea pig Ercc2 (100721308), naked mole-rat Ercc2 (101697378), sheep ERCC2 (101116341), Domestic Rabbit ERCC2 (100347957), Zebrafish ercc2 (393900), cow ERCC2 (100125238), domestic cat ERCC2 (101095702)
UniProtKB ID:
Gene ID:
- Human(2068) Summary: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(13871) excision repair cross-complementing rodent repair deficiency, complementation group 2
- Rat(308415) excision repair cross-complementing rodent repair deficiency, complementation group 2
- domestic guinea pig(100721308) excision repair cross-complementing rodent repair deficiency, complementation group 2
- naked mole-rat(101697378) excision repair cross-complementing rodent repair deficiency, complementation group 2
- sheep(101116341) excision repair cross-complementing rodent repair deficiency, complementation group 2
- Domestic Rabbit(100347957) excision repair cross-complementing rodent repair deficiency, complementation group 2
- Zebrafish(393900) excision repair cross-complementing rodent repair deficiency, complementation group 2
- cow(100125238) excision repair cross-complementing rodent repair deficiency, complementation group 2
- domestic cat(101095702) excision repair cross-complementing rodent repair deficiency, complementation group 2
- dog(493995) excision repair cross-complementing rodent repair deficiency, complementation group 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-XPD Antibody, clone 22TF2-2F6, clone 22TF2-2F6, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-ERCC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-ERCC2 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunofluorescence
Anti-ERCC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Proteins
Product Number
Description
Species