DYSF
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
Synonymes:
FER1L1, LGMD2B, MMD1
Espèce(s):
Human DYSF (8291), Mouse Dysf (26903), Rat Dysf (312492), sheep DYSF (101109257), Domestic Rabbit DYSF (100342946), domestic guinea pig Dysf (100720513), naked mole-rat Dysf (101715575), Zebrafish dysf (560924), chicken DYSF (425353), cow DYSF (508157) ...Plus
ID UniProtKB:
ID du gène:
- Human(8291) Summary: The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008]
- Mouse(26903) dysferlin
- Rat(312492) dysferlin
- sheep(101109257) dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
- Domestic Rabbit(100342946) dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
- domestic guinea pig(100720513) dysferlin
- naked mole-rat(101715575) dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
- Zebrafish(560924) dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
- chicken(425353) dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
- cow(508157) dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
- domestic cat(101099290) dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
- dog(483121) dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-DYSF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Dysferlin (Romeo) antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-DYSF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-Dysferlin/DYSF Antibody, clone 10H3.1, clone 10H3.1, from mouse,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-Dysferlin, antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
western blot
western blot