DUSP2
dual specificity phosphatase 2
Synonyms:
PAC-1, PAC1
Species:
Human DUSP2 (1844), Mouse Dusp2 (13537), Rat Dusp2 (311406), domestic guinea pig Dusp2 (100723186), naked mole-rat Dusp2 (101702046), sheep DUSP2 (101115699), Zebrafish dusp2 (445057), dog DUSP2 (611653), cow DUSP2 (539140), domestic cat DUSP2 (101090684)
UniProtKB ID:
Gene ID:
- Human(1844) Summary: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq, Jul 2008]
- Mouse(13537) dual specificity phosphatase 2
- Rat(311406) dual specificity phosphatase 2
- domestic guinea pig(100723186) dual specificity phosphatase 2
- naked mole-rat(101702046) dual specificity phosphatase 2
- sheep(101115699) dual specificity phosphatase 2
- Zebrafish(445057) dual specificity phosphatase 2
- dog(611653) dual specificity phosphatase 2
- cow(539140) dual specificity phosphatase 2
- domestic cat(101090684) dual specificity phosphatase 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DUSP2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-DUSP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence