DPYD
dihydropyrimidine dehydrogenase
Synonyms:
DHP, DHPDHASE, DPD
Species:
Human DPYD (1806), Mouse Dpyd (99586), Rat Dpyd (81656), sheep DPYD (101109311), domestic guinea pig Dpyd (100727906), naked mole-rat Dpyd (101704452), chicken DPYD (429083), cow DPYD (281124), Horse DPYD (100057177), domestic cat DPYD (101084380)
UniProtKB ID:
Gene ID:
- Human(1806) Summary: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
- Mouse(99586) dihydropyrimidine dehydrogenase
- Rat(81656) dihydropyrimidine dehydrogenase
- sheep(101109311) dihydropyrimidine dehydrogenase
- domestic guinea pig(100727906) dihydropyrimidine dehydrogenase
- naked mole-rat(101704452) dihydropyrimidine dehydrogenase
- chicken(429083) dihydropyrimidine dehydrogenase
- cow(281124) dihydropyrimidine dehydrogenase
- Horse(100057177) dihydropyrimidine dehydrogenase
- domestic cat(101084380) dihydropyrimidine dehydrogenase
- dog(479935) dihydropyrimidine dehydrogenase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DPYD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-DPYD Mouse mAb (7D4), liquid, clone 7D4, Calbiochem®,
Species Reactivity
human
Application
Anti-Dihydropyrimidine dehydrogenase/DPYD Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, horse, human, porcine, primate
Application
immunohistochemistry
western blot
western blot
esiRNA
Product Number
Description
Species