DPH5
diphthamide biosynthesis 5
Synonyms:
CGI-30, HSPC143, NPD015
Species:
Human DPH5 (51611), Mouse Dph5 (69740), Rat Dph5 (295394), Zebrafish dph5 (492514), cow DPH5 (508904), domestic cat DPH5 (101090957), dog DPH5 (612092), fruit fly Dph5 (42663), chicken DPH5 (424463), Zebrafish dph5 (100003898) ...More
UniProtKB ID:
Gene ID:
- Human(51611) Summary: This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(69740) DPH5 homolog (S. cerevisiae)
- Rat(295394) diphthamide biosynthesis 5
- Zebrafish(492514) DPH5 homolog (S. cerevisiae)
- cow(508904) DPH5 homolog (S. cerevisiae)
- domestic cat(101090957) DPH5 homolog (S. cerevisiae)
- dog(612092) DPH5 homolog (S. cerevisiae)
- fruit fly(42663) Diphthamide methyltransferase
- chicken(424463) DPH5 homolog (S. cerevisiae)
- Zebrafish(100003898) DPH5 homolog (S. cerevisiae)
- sheep(101115329) DPH5 homolog (S. cerevisiae)
- domestic guinea pig(100732624) diphthamide biosynthesis 5
- naked mole-rat(101696986) diphthamide biosynthesis 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DPH5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-DPH5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-DPH5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence