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Merck

DNM2

dynamin 2

Sinónimos:
CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5
Especie:
ID UniProtKB:
ID del gen:
  • Human(1785) Summary: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
  • Mouse(13430) dynamin 2
  • Rat(25751) dynamin 2
  • dog(484949) dynamin 2
  • cow(511691) dynamin 2
  • domestic cat(101100788) dynamin 2
  • sheep(101115027) dynamin 2
  • domestic guinea pig(100717689) dynamin 2
  • naked mole-rat(101696596) dynamin 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DNM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-Dynamin 2 (DNM2) antibody produced in mouse, clone DYN2-11, purified from hybridoma cell culture,
Reactividad de especies
Aplicación
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-phospho-Dynamin (pSer778) antibody produced in sheep, affinity isolated antibody, aqueous glycerol suspension,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-phospho-Dynamin (pSer774) antibody produced in sheep, affinity isolated antibody, aqueous glycerol suspension,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Dnm2,
Especie
mouse