DMGDH
dimethylglycine dehydrogenase
Synonyms:
DMGDHD, ME2GLYDH
Species:
Human DMGDH (29958), Mouse Dmgdh (74129), Rat Dmgdh (245961), Zebrafish dmgdh (100141496), cow DMGDH (504453), Horse DMGDH (100073267), domestic cat DMGDH (101089168), dog DMGDH (488935), chicken DMGDH (416370), sheep DMGDH (101113594) ...More
UniProtKB ID:
Gene ID:
- Human(29958) Summary: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. [provided by RefSeq, Jul 2008]
- Mouse(74129) dimethylglycine dehydrogenase precursor
- Rat(245961) dimethylglycine dehydrogenase
- Zebrafish(100141496) dimethylglycine dehydrogenase
- cow(504453) dimethylglycine dehydrogenase
- Horse(100073267) dimethylglycine dehydrogenase
- domestic cat(101089168) dimethylglycine dehydrogenase
- dog(488935) dimethylglycine dehydrogenase
- chicken(416370) dimethylglycine dehydrogenase
- sheep(101113594) dimethylglycine dehydrogenase
- Domestic Rabbit(100340207) dimethylglycine dehydrogenase
- domestic guinea pig(100724353) dimethylglycine dehydrogenase
- naked mole-rat(101722315) dimethylglycine dehydrogenase
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