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DDB2

damage-specific DNA binding protein 2, 48kDa

Synonyms:
DDBB, UV-DDB2
Species:
UniProtKB ID:
Gene ID:
  • Human(1643) Summary: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. [provided by RefSeq, Jul 2008]
  • Mouse(107986) damage specific DNA binding protein 2
  • Rat(100362121) damage specific DNA binding protein 2
  • Zebrafish(100004133) damage-specific DNA binding protein 2
  • chicken(423185) damage-specific DNA binding protein 2, 48kDa
  • Thale Cress(835990) DNA damage-binding protein 2
  • cow(519357) damage-specific DNA binding protein 2, 48kDa
  • Horse(100051180) damage-specific DNA binding protein 2, 48kDa
  • domestic cat(101092211) damage-specific DNA binding protein 2, 48kDa
  • dog(483626) damage-specific DNA binding protein 2, 48kDa
  • sheep(101116344) damage-specific DNA binding protein 2, 48kDa
  • Domestic Rabbit(100352386) damage-specific DNA binding protein 2, 48kDa
  • naked mole-rat(101715591) damage-specific DNA binding protein 2, 48kDa
  • domestic guinea pig(100726538) damage-specific DNA binding protein 2, 48kDa

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DDB2 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Anti-DDB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ddb2,
Species
mouse
MISSION® esiRNA, targeting human DDB2,
Species
human