DDB2
damage-specific DNA binding protein 2, 48kDa
DDBB, UV-DDB2
Human DDB2 (1643), Mouse Ddb2 (107986), Rat Ddb2 (100362121), Zebrafish ddb2 (100004133), chicken DDB2 (423185), Thale Cress DDB2 (835990), cow DDB2 (519357), Horse DDB2 (100051180), domestic cat DDB2 (101092211), dog DDB2 (483626) ...More
- Human(1643) Summary: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. [provided by RefSeq, Jul 2008]
- Mouse(107986) damage specific DNA binding protein 2
- Rat(100362121) damage specific DNA binding protein 2
- Zebrafish(100004133) damage-specific DNA binding protein 2
- chicken(423185) damage-specific DNA binding protein 2, 48kDa
- Thale Cress(835990) DNA damage-binding protein 2
- cow(519357) damage-specific DNA binding protein 2, 48kDa
- Horse(100051180) damage-specific DNA binding protein 2, 48kDa
- domestic cat(101092211) damage-specific DNA binding protein 2, 48kDa
- dog(483626) damage-specific DNA binding protein 2, 48kDa
- sheep(101116344) damage-specific DNA binding protein 2, 48kDa
- Domestic Rabbit(100352386) damage-specific DNA binding protein 2, 48kDa
- naked mole-rat(101715591) damage-specific DNA binding protein 2, 48kDa
- domestic guinea pig(100726538) damage-specific DNA binding protein 2, 48kDa
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immunofluorescence
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immunohistochemistry