DCTN2
dynactin 2 (p50)
Synonyms:
DCTN50, DYNAMITIN, RBP50
Species:
Human DCTN2 (10540), Mouse Dctn2 (69654), Rat Dctn2 (299850), Zebrafish dctn2 (394141), cow DCTN2 (527201), Horse DCTN2 (100050464), domestic cat DCTN2 (101093950), dog DCTN2 (474415), chicken DCTN2 (395587), naked mole-rat Dctn2 (101713049) ...More
UniProtKB ID:
Gene ID:
- Human(10540) Summary: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]
- Mouse(69654) dynactin 2
- Rat(299850) dynactin 2 (p50)
- Zebrafish(394141) dynactin 2 (p50)
- cow(527201) dynactin 2 (p50)
- Horse(100050464) dynactin 2 (p50)
- domestic cat(101093950) dynactin 2 (p50)
- dog(474415) dynactin 2 (p50)
- chicken(395587) dynactin 2 (p50)
- naked mole-rat(101713049) dynactin 2 (p50)
- domestic guinea pig(100721002) dynactin 2 (p50)
- sheep(101119807) dynactin 2 (p50)
- Domestic Rabbit(100339187) dynactin 2 (p50)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DCTN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-DCTN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-DCTN2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Monoclonal Anti-DCTN2 antibody produced in mouse, clone 2G7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot