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Merck

CYBB

cytochrome b-245, beta polypeptide

別名:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Mouse(13058) cytochrome b-245, beta polypeptide
  • Rat(66021) cytochrome b-245, beta polypeptide
  • Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • chicken(418581) cytochrome b-245, beta polypeptide
  • cow(281112) cytochrome b-245, beta polypeptide
  • dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • sheep(100036757) cytochrome b-245, beta polypeptide
  • Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-gp91-phox Antibody, Upstate®, from rabbit,
交差性
human
アプリケーション
western blot
Anti-CYBB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rabbit, rat
アプリケーション
western blot
Anti-gp91phox (NOX2) Antibody, ,
交差性
human
アプリケーション
flow cytometry
western blot
Anti-gp91phox (NOX2) Antibody, ,
交差性
human
アプリケーション
flow cytometry
inhibition assay

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CYBB,
Species
human