CYB5R3
cytochrome b5 reductase 3
Synonyms:
B5R, DIA1
Species:
Human CYB5R3 (1727), Mouse Cyb5r3 (109754), Rat Cyb5r3 (25035), Zebrafish cyb5r3 (324560), cow CYB5R3 (515773), dog CYB5R3 (474479), chicken CYB5R3 (418220)
UniProtKB ID:
Gene ID:
- Human(1727) Summary: This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
- Mouse(109754) cytochrome b5 reductase 3
- Rat(25035) cytochrome b5 reductase 3
- Zebrafish(324560) cytochrome b5 reductase 3
- cow(515773) cytochrome b5 reductase 3
- dog(474479) cytochrome b5 reductase 3
- chicken(418220) cytochrome b5 reductase 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CYB5R3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CYB5R3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-CYB5R3 Antibody, clone 1D9.2, clone 1D9.2, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-CYB5R3 antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-Cyb5r3 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, mouse, rat
Application
ELISA
western blot
western blot