CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
Synonyms:
CTNNB, MRD19, armadillo
Species:
Human CTNNB1 (1499), Mouse Ctnnb1 (12387), Rat Ctnnb1 (84353), naked mole-rat Ctnnb1 (101720578), domestic guinea pig Ctnnb1 (100732604), sheep CTNNB1 (100294600), Domestic Rabbit CTNNB1 (100125985), Zebrafish ctnnb1 (30265), chicken CTNNB1 (395964), cow CTNNB1 (539003) ...More
UniProtKB ID:
Gene ID:
- Human(1499) Summary: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
- Mouse(12387) catenin (cadherin associated protein), beta 1
- Rat(84353) catenin (cadherin associated protein), beta 1
- naked mole-rat(101720578) catenin (cadherin-associated protein), beta 1, 88kDa
- domestic guinea pig(100732604) catenin (cadherin-associated protein), beta 1, 88kDa
- sheep(100294600) catenin (cadherin-associated protein), beta 1, 88kDa
- Domestic Rabbit(100125985) catenin (cadherin-associated protein), beta 1, 88kDa
- Zebrafish(30265) catenin (cadherin-associated protein), beta 1
- chicken(395964) catenin (cadherin-associated protein), beta 1, 88kDa
- cow(539003) catenin (cadherin-associated protein), beta 1, 88kDa
- Horse(100055241) catenin (cadherin-associated protein), beta 1, 88kDa
- domestic cat(101097342) catenin (cadherin-associated protein), beta 1, 88kDa
- dog(477032) catenin (cadherin-associated protein), beta 1, 88kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Phospho-beta Catenin-S552 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Phospho-CTNNB1-S45 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Phospho-β-Catenin-S33/S37 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
western blot
Anti- β-Catenin antibody produced in mouse, ,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-β-Catenin antibody produced in mouse, clone 15B8, ascites fluid,
Species Reactivity
bovine, canine, chicken, human
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
microarray
western blot
immunofluorescence
immunohistochemistry
microarray
western blot
Proteins
Product Number
Description
Species
Catenin β, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human