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Merck

CLCNKB

chloride channel, voltage-sensitive Kb

Synonyms:
CLCKB, ClC-K2, ClC-Kb
Species:
Human CLCNKB (1188), Mouse Clcnkb (56365), Rat Clcnkb (79430), chicken CLCNKB (428190), dog CLCNKB (487422), domestic guinea pig Clcnkb (100730738)
UniProtKB ID:
P51801, B3KUY3, Q5T5Q7, Q5T5Q8
Gene ID:
  • Human(1188) Summary: The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(56365) chloride channel Kb
  • Rat(79430) chloride channel, voltage-sensitive Kb
  • chicken(428190) chloride channel, voltage-sensitive Kb
  • dog(487422) chloride channel, voltage-sensitive Kb
  • domestic guinea pig(100730738) chloride channel, voltage-sensitive Kb

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