CENPB
centromere protein B, 80kDa
Human CENPB (1059), Mouse Cenpb (12616), Rat Cenpb (362217), naked mole-rat Cenpb (101700720), domestic guinea pig Cenpb (100713491), sheep CENPB (101110697), cow CENPB (281680), dog CENPB (485791), cow CENPB (788381), domestic cat CENPB (101093012)
- Human(1059) Summary: This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008]
- Mouse(12616) centromere protein B
- Rat(362217) centromere protein B
- naked mole-rat(101700720) centromere protein B, 80kDa
- domestic guinea pig(100713491) centromere protein B, 80kDa
- sheep(101110697) centromere protein B, 80kDa
- cow(281680) centromere protein B, 80kDa
- dog(485791) centromere protein B, 80kDa
- cow(788381) centromere protein B, 80kDa
- domestic cat(101093012) centromere protein B, 80kDa
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Antibodies
Anti-CENPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
human
immunofluorescence
Anti-CENPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
human
immunofluorescence