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Merck

CENPB

centromere protein B, 80kDa

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(1059) Summary: This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008]
  • Mouse(12616) centromere protein B
  • Rat(362217) centromere protein B
  • naked mole-rat(101700720) centromere protein B, 80kDa
  • domestic guinea pig(100713491) centromere protein B, 80kDa
  • sheep(101110697) centromere protein B, 80kDa
  • cow(281680) centromere protein B, 80kDa
  • dog(485791) centromere protein B, 80kDa
  • cow(788381) centromere protein B, 80kDa
  • domestic cat(101093012) centromere protein B, 80kDa

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CENPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CENPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cenpb,
Species
mouse