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Merck

CDKN1C

cyclin-dependent kinase inhibitor 1C (p57, Kip2)

동의어:
BWCR, BWS, KIP2, WBS, p57, p57Kip2
:
UniProtKB ID:
Clone ID:
  • Human(1028) Summary: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
  • Mouse(12577) cyclin-dependent kinase inhibitor 1C (P57)
  • Rat(246060) cyclin-dependent kinase inhibitor 1C
  • Zebrafish(399483) cyclin-dependent kinase inhibitor 1C
  • cow(510972) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • sheep(100216434) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • naked mole-rat(101726530) cyclin-dependent kinase inhibitor 1C (p57, Kip2)

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-p57 KIP2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
ELISA
immunofluorescence

western blot
Anti-CDKN1C/p57 Kip2 Antibody, clone 6T4E6, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
western blot
Anti-CDKN1C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-Kip2 Antibody, Upstate®, from rabbit,
종별 반응성
bovine, human
응용분야
immunoprecipitation (IP)
western blot
Anti-p57Kip2 Antibody, clone 1H11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, mouse, rat
응용분야
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
Roscovitine, ≥98% (TLC),
human, mouse, rat
Olomoucine, ≥98% (HPLC),
human, rat

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Cdkn1c,
mouse