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Merck

CDK9

cyclin-dependent kinase 9

同義詞:
C-2k, CDC2L4, CTK1, PITALRE, TAK
物種:
UniProtKB ID:
基因 ID:
  • Human(1025) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
  • Mouse(107951) cyclin-dependent kinase 9 (CDC2-related kinase)
  • Rat(362110) cyclin-dependent kinase 9
  • Zebrafish(321602) cyclin-dependent kinase 9 (CDC2-related kinase)
  • chicken(417226) cyclin-dependent kinase 9
  • fruit fly(37586) Cyclin-dependent kinase 9
  • dog(491325) cyclin-dependent kinase 9
  • cow(520580) cyclin-dependent kinase 9
  • domestic cat(101097767) cyclin-dependent kinase 9
  • naked mole-rat(101722666) cyclin-dependent kinase 9
  • domestic guinea pig(100725846) cyclin-dependent kinase 9
  • sheep(101109788) cyclin-dependent kinase 9

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Antibodies

產品編號
描述
物種活性
應用
Anti-CDK9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
immunohistochemistry
western blot
Anti-phospho-CDK9 (pThr186) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
Rabbit anti-CDK9 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物種活性
human, mouse
應用
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
夫拉平度 盐酸盐, ≥98% (HPLC), powder,
物種
human
核抑制剂, ≥98% (TLC),
物種
human, mouse, rat
奥罗莫星, ≥98% (HPLC),
物種
human, rat

Proteins

產品編號
描述
物種
Cdk9/Cyclin T1 Protein, active, 10 µg, Active, C-terminal 6His-tagged, full length recombinant, human Cdk9 co-expressed with untagged, full-length human Cyclin T1, for use in Kinase Assays.,
物種
human
CDK9/CyclinK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human