CDC27
cell division cycle 27
Synonyms:
ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2
Species:
Human CDC27 (996), Mouse Cdc27 (217232), Rat Cdc27 (360643), Zebrafish cdc27 (30450), cow CDC27 (540660), Horse CDC27 (100054552), chicken CDC27 (419960), domestic cat CDC27 (101091234), dog CDC27 (490924), fruit fly Cdc27 (38798) ...More
UniProtKB ID:
Gene ID:
- Human(996) Summary: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(217232) cell division cycle 27
- Rat(360643) cell division cycle 27
- Zebrafish(30450) cell division cycle 27
- cow(540660) cell division cycle 27 homolog (S. cerevisiae)
- Horse(100054552) cell division cycle 27 homolog (S. cerevisiae)
- chicken(419960) cell division cycle 27 homolog (S. cerevisiae)
- domestic cat(101091234) cell division cycle 27 homolog (S. cerevisiae)
- dog(490924) cell division cycle 27 homolog (S. cerevisiae)
- fruit fly(38798) CG8610 gene product from transcript CG8610-RB
- sheep(101121276) cell division cycle 27 homolog (S. cerevisiae)
- domestic guinea pig(100731091) cell division cycle 27
- naked mole-rat(101717421) cell division cycle 27
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-H-NUC antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APC3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CDC27 Antibody, clone 7U5A3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot