CDC25A
cell division cycle 25A
Synonyms:
CDC25A2
Species:
Human CDC25A (993), Mouse Cdc25a (12530), Rat Cdc25a (171102), chicken CDC25A (420375), cow CDC25A (520188), Horse CDC25A (100064223), domestic cat CDC25A (101098445), dog CDC25A (484780), sheep CDC25A (101113178), domestic guinea pig Cdc25a (100721008)
UniProtKB ID:
Gene ID:
- Human(993) Summary: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12530) cell division cycle 25A
- Rat(171102) cell division cycle 25A
- chicken(420375) cell division cycle 25 homolog A (S. pombe)
- cow(520188) cell division cycle 25 homolog A (S. pombe)
- Horse(100064223) cell division cycle 25 homolog A (S. pombe)
- domestic cat(101098445) cell division cycle 25 homolog A (S. pombe)
- dog(484780) cell division cycle 25 homolog A (S. pombe)
- sheep(101113178) cell division cycle 25 homolog A (S. pombe)
- domestic guinea pig(100721008) cell division cycle 25A
- naked mole-rat(101699133) cell division cycle 25A
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-CDC25A (pSer124) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Phospho-CDC25A-S76 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-phospho-CDC25A (pSer178) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-CDC25A (pSer124) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-Cdc25A Antibody, clone 1M11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
CDC25A, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human