CD40
CD40 molecule, TNF receptor superfamily member 5
Synonyms:
Bp50, CDW40, TNFRSF5, p50
Species:
Human CD40 (958), Mouse Cd40 (21939), Rat Cd40 (171369), Zebrafish cd40 (100270764), cow CD40 (286849), Horse CD40 (100034049), domestic cat CD40 (101085363), dog CD40 (403469), chicken CD40 (395385), sheep CD40 (443232) ...More
UniProtKB ID:
Gene ID:
- Human(958) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(21939) CD40 antigen
- Rat(171369) CD40 molecule, TNF receptor superfamily member 5
- Zebrafish(100270764) CD40 antigen
- cow(286849) CD40 molecule, TNF receptor superfamily member 5
- Horse(100034049) CD40 molecule, TNF receptor superfamily member 5
- domestic cat(101085363) CD40 molecule, TNF receptor superfamily member 5
- dog(403469) CD40 molecule, TNF receptor superfamily member 5
- chicken(395385) CD40 molecule, TNF receptor superfamily member 5
- sheep(443232) CD40 molecule, TNF receptor superfamily member 5
- naked mole-rat(101715501) CD40 molecule, TNF receptor superfamily member 5
- domestic guinea pig(100728791) CD40 molecule, TNF receptor superfamily member 5
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-TNFRSF5 (pThr254) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-CD40 Antibody, clone 5V8X7, Rabbit Monoclonal, ,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD40 antibody produced in mouse, clone 1G1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-CD40-FITC antibody produced in mouse, clone HI40a, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Anti-CD40 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot