Skip to Content
Merck

CAMKK2

calcium/calmodulin-dependent protein kinase kinase 2, beta

Synonyms:
CAMKK, CAMKKB
Species:
Human CAMKK2 (10645), Mouse Camkk2 (207565), Rat Camkk2 (83506), naked mole-rat Camkk2 (101723556), domestic guinea pig Camkk2 (100716041), sheep CAMKK2 (101103267), chicken CAMKK2 (396405), dog CAMKK2 (486263), cow CAMKK2 (509084), domestic cat CAMKK2 (101097674)
UniProtKB ID:
Q96RR4, A8K7Q7, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04
Gene ID:
  • Human(10645) Summary: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
  • Mouse(207565) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • Rat(83506) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • naked mole-rat(101723556) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • domestic guinea pig(100716041) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • sheep(101103267) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • chicken(396405) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • dog(486263) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • cow(509084) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • domestic cat(101097674) calcium/calmodulin-dependent protein kinase kinase 2, beta

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.