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Merck

BCL11A

B-cell CLL/lymphoma 11A (zinc finger protein)

Synonymes:
BCL11A-L, BCL11A-S, BCL11A-XL, BCL11a-M, CTIP1, EVI9, HBFQTL5, ZNF856
Espèce(s):
Human BCL11A (53335), Mouse Bcl11a (14025), Rat Bcl11a (305589), domestic guinea pig Bcl11a (100734801), sheep BCL11A (101119124), Domestic Rabbit BCL11A (100355522), chicken BCL11A (421199), cow BCL11A (538680), domestic cat BCL11A (101098704), dog BCL11A (481381)
ID UniProtKB:
Q9H165, D6W5D7, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9
ID du gène:
  • Human(53335) Summary: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14025) B cell CLL/lymphoma 11A (zinc finger protein)
  • Rat(305589) B-cell CLL/lymphoma 11A (zinc finger protein)
  • domestic guinea pig(100734801) B-cell CLL/lymphoma 11A (zinc finger protein)
  • sheep(101119124) B-cell CLL/lymphoma 11A (zinc finger protein)
  • Domestic Rabbit(100355522) B-cell CLL/lymphoma 11A (zinc finger protein)
  • chicken(421199) B-cell CLL/lymphoma 11A (zinc finger protein)
  • cow(538680) B-cell CLL/lymphoma 11A (zinc finger protein)
  • domestic cat(101098704) B-cell CLL/lymphoma 11A (zinc finger protein)
  • dog(481381) B-cell CLL/lymphoma 11A (zinc finger protein)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
ZRB1518
Anti-Bcl11A Antibody, clone 2C4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
SAB2100215
Anti-BCL11A antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, horse, human, mouse, pig, rat
Application
immunohistochemistry
western blot
SAB1400573
Monoclonal Anti-BCL11A antibody produced in mouse, clone 3D9, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
western blot
SAB5702769
Anti-CTIP1/BCL11A Antibody, clone 3M8M3, Rabbit Monoclonal, ,
Espèces réactives
human, rat
Application
immunohistochemistry
western blot
AMAB91871
Monoclonal Anti-Bcl11A Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13530, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EHU145981
MISSION® esiRNA, targeting human BCL11A,
Espèce(s)
human
EMU071531
MISSION® esiRNA, targeting mouse Bcl11a,
Espèce(s)
mouse