BAX
BCL2-associated X protein
Synonyms:
BCL2L4
Species:
Human BAX (581), Mouse Bax (12028), Rat Bax (24887), naked mole-rat Bax (101713575), domestic guinea pig Bax (100730890), Goat BAX (100846984), sheep BAX (443059), dog BAX (403523), domestic cat BAX (493837), cow BAX (280730)
UniProtKB ID:
Gene ID:
- Human(581) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12028) BCL2-associated X protein
- Rat(24887) Bcl2-associated X protein
- naked mole-rat(101713575) BCL2-associated X protein
- domestic guinea pig(100730890) BCL2-associated X protein
- Goat(100846984) BCL2-associated X protein
- sheep(443059) BCL2-associated X protein
- dog(403523) BCL2-associated X protein
- domestic cat(493837) BCL2-associated X protein
- cow(280730) BCL2-associated X protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Bax Antibody, NT, aa3-16 hBax protein, clone 2D2, clone 2D2, Chemicon®, from mouse,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Bax (NT) Antibody, from rabbit,
Species Reactivity
bovine, canine, chimpanzee, feline, human, rhesus monkey
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Monoclonal Anti-BAX antibody produced in mouse, clone 1F5-1B7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
Anti-BAX antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-BAX antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Cell Lines
Proteins
Product Number
Description
Species
BAX, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species