Skip to Content
MilliporeSigma

BAP1

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

Synonyms:
HUCEP-13, UCHL2
Species:
UniProtKB ID:
Gene ID:
  • Human(8314) Summary: This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
  • Mouse(104416) Brca1 associated protein 1
  • Rat(306257) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Zebrafish(558885) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • cow(100124510) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Horse(100051934) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • domestic cat(101092671) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • dog(484737) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • chicken(415944) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Thale Cress(825291) BON association protein 1
  • naked mole-rat(101703932) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • domestic guinea pig(100731081) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • sheep(101111666) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Rabbit anti-BAP1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
Anti-BAP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-BAP1 Antibody, clone 3C11, clone 3C11, from mouse,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
Anti-BAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-BAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Bap1,
Species
mouse
MISSION® esiRNA, targeting human BAP1,
Species
human