Skip to Content
MilliporeSigma

ATP6V0A1

ATPase, H+ transporting, lysosomal V0 subunit a1

Synonyms:
ATP6N1, ATP6N1A, Stv1, VPP1, Vph1, a1
Species:
Human ATP6V0A1 (535), Mouse Atp6v0a1 (11975), Rat Atp6v0a1 (29757), Zebrafish atp6v0a1 (100332691), cow ATP6V0A1 (286768), Horse ATP6V0A1 (100052802), domestic cat ATP6V0A1 (101096367), dog ATP6V0A1 (607705), chicken ATP6V0A1 (395474), sheep ATP6V0A1 (101123476) ...More
UniProtKB ID:
Q93050, B7Z3B7, Q8N5G7, Q9NSX0
Gene ID:
  • Human(535) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11975) ATPase, H+ transporting, lysosomal V0 subunit A1
  • Rat(29757) ATPase, H+ transporting, lysosomal V0 subunit A1
  • Zebrafish(100332691) ATPase, H+ transporting, lysosomal V0 subunit a1
  • cow(286768) ATPase, H+ transporting, lysosomal V0 subunit a1
  • Horse(100052802) ATPase, H+ transporting, lysosomal V0 subunit a1
  • domestic cat(101096367) ATPase, H+ transporting, lysosomal V0 subunit a1
  • dog(607705) ATPase, H+ transporting, lysosomal V0 subunit a1
  • chicken(395474) ATPase, H+ transporting, lysosomal V0 subunit a1
  • sheep(101123476) ATPase, H+ transporting, lysosomal V0 subunit a1
  • domestic guinea pig(100717816) ATPase, H+ transporting, lysosomal V0 subunit a1
  • naked mole-rat(101718747) ATPase, H+ transporting, lysosomal V0 subunit a1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
SAB2108042
Anti-ATP6V0A1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
HPA022144
Anti-ATP6V0A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
SAB2105330
Anti-ATP6V0A1, (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, mouse, pig, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU080771
MISSION® esiRNA, targeting mouse Atp6v0a1,
Species
mouse
EHU157271
MISSION® esiRNA, targeting human ATP6V0A1,
Species
human