ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
Synonyms:
ASP, Calmbp1, MCPH5
Species:
Human ASPM (259266), Mouse Aspm (12316), Rat Aspm (289054), naked mole-rat Aspm (101714580), domestic guinea pig Aspm (100713679), sheep ASPM (443284), Zebrafish aspm (554173), cow ASPM (534849), domestic cat ASPM (493695), dog ASPM (480009)
UniProtKB ID:
Gene ID:
- Human(259266) Summary: This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
- Mouse(12316) asp (abnormal spindle)-like, microcephaly associated (Drosophila)
- Rat(289054) asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
- naked mole-rat(101714580) asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
- domestic guinea pig(100713679) asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
- sheep(443284) asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
- Zebrafish(554173) asp (abnormal spindle)-like, microcephaly associated (Drosophila)
- cow(534849) asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
- domestic cat(493695) asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
- dog(480009) asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
- chicken(424354) asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
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