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MilliporeSigma

ARRB2

arrestin, beta 2

Synonyms:
ARB2, ARR2, BARR2
Species:
UniProtKB ID:
Gene ID:
  • Human(409) Summary: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
  • Mouse(216869) arrestin, beta 2
  • Rat(25388) arrestin, beta 2
  • domestic guinea pig(100716149) arrestin, beta 2
  • naked mole-rat(101709908) arrestin, beta 2
  • sheep(101112493) arrestin, beta 2
  • Domestic Rabbit(100341204) arrestin, beta 2
  • Horse(100072892) arrestin, beta 2
  • domestic cat(101093558) arrestin, beta 2
  • dog(607262) arrestin, beta 2
  • cow(281638) arrestin, beta 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ARRB2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, pig, rabbit, rat
Application
immunohistochemistry
western blot
Anti-ARRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ARRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-Arrestin β2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-ARRB2 antibody produced in mouse, clone 3G1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

proximity ligation assay

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ARRB2,
Species
human
MISSION® esiRNA, targeting mouse Arrb2,
Species
mouse