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APPL1

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

Synonyms:
APPL, DIP13alpha
Species:
UniProtKB ID:
Gene ID:
  • Human(26060) Summary: The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
  • Mouse(72993) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Rat(290537) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Zebrafish(571540) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • chicken(416002) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • domestic cat(101096960) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • cow(517850) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Horse(100058653) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • dog(484716) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • naked mole-rat(101703342) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • domestic guinea pig(100724445) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • sheep(101109218) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Domestic Rabbit(100353097) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-APPL1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Ani-APPL1 Antibody, clone 2K17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
ANTI-APPL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-APPL1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
Anti-APPL1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Appl1,
Species
mouse
MISSION® esiRNA, targeting human APPL1,
Species
human