APLP1
amyloid beta (A4) precursor-like protein 1
Synonyms:
APLP
Species:
Human APLP1 (333), Mouse Aplp1 (11803), Rat Aplp1 (502317), Zebrafish aplp1 (404233), dog APLP1 (476478), Horse APLP1 (100060016), cow APLP1 (513154), domestic cat APLP1 (101097529), sheep APLP1 (101105352), domestic guinea pig Aplp1 (100725457)
UniProtKB ID:
Gene ID:
- Human(333) Summary: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11803) amyloid beta (A4) precursor-like protein 1
- Rat(502317) amyloid beta (A4) precursor-like protein 1
- Zebrafish(404233) amyloid beta (A4) precursor-like protein 1
- dog(476478) amyloid beta (A4) precursor-like protein 1
- Horse(100060016) amyloid beta (A4) precursor-like protein 1
- cow(513154) amyloid beta (A4) precursor-like protein 1
- domestic cat(101097529) amyloid beta (A4) precursor-like protein 1
- sheep(101105352) amyloid beta (A4) precursor-like protein 1
- domestic guinea pig(100725457) amyloid beta (A4) precursor-like protein 1
- naked mole-rat(101706550) amyloid beta (A4) precursor-like protein 1
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