APH1B
APH1B gamma secretase subunit
Synonyms:
APH-1B, PRO1328, PSFL, TAAV688
Species:
Human APH1B (83464), Mouse Aph1b (208117), Rat Aph1b (300802), sheep APH1B (101111553), naked mole-rat Aph1b (101712646), domestic guinea pig Aph1b (100718283), Zebrafish aph1b (386808), dog APH1B (487589), Horse APH1B (100067205), cow APH1B (530913)
UniProtKB ID:
Gene ID:
- Human(83464) Summary: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]
- Mouse(208117) anterior pharynx defective 1b homolog (C. elegans)
- Rat(300802) anterior pharynx defective 1 homolog B (C. elegans)
- sheep(101111553) anterior pharynx defective 1 homolog B (C. elegans)
- naked mole-rat(101712646) APH1B gamma secretase subunit
- domestic guinea pig(100718283) APH1B gamma secretase subunit
- Zebrafish(386808) anterior pharynx defective 1B
- dog(487589) anterior pharynx defective 1 homolog B (C. elegans)
- Horse(100067205) anterior pharynx defective 1 homolog B (C. elegans)
- cow(530913) anterior pharynx defective 1 homolog B (C. elegans)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-APH1B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot