APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Synonyms:
FE65, MGC:9072, RIR
Species:
Human APBB1 (322), Mouse Apbb1 (11785), Rat Apbb1 (29722), Domestic Rabbit APBB1 (100354159), naked mole-rat Apbb1 (101699658), domestic guinea pig Apbb1 (100735070), Zebrafish apbb1 (565164), dog APBB1 (476833), cow APBB1 (505096), Horse APBB1 (100069964) ...More
UniProtKB ID:
Gene ID:
- Human(322) Summary: The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
- Mouse(11785) amyloid beta (A4) precursor protein-binding, family B, member 1
- Rat(29722) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- Domestic Rabbit(100354159) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- naked mole-rat(101699658) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- domestic guinea pig(100735070) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- Zebrafish(565164) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- dog(476833) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- cow(505096) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- Horse(100069964) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- domestic cat(101090045) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- chicken(100859045) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Fe65 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
mouse
Application
western blot
Anti-APBB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-APBB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-APBB1/FE65 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-APBB1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot