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ADAM15

ADAM metallopeptidase domain 15

Synonyms:
MDC15
Species:
UniProtKB ID:
Gene ID:
  • Human(8751) Summary: The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(11490) a disintegrin and metallopeptidase domain 15 (metargidin)
  • Rat(57025) ADAM metallopeptidase domain 15
  • chicken(419050) ADAM metallopeptidase domain 15
  • Horse(100063219) ADAM metallopeptidase domain 15
  • cow(784605) ADAM metallopeptidase domain 15
  • domestic cat(101095312) ADAM metallopeptidase domain 15
  • dog(490434) ADAM metallopeptidase domain 15
  • sheep(101105128) ADAM metallopeptidase domain 15
  • Domestic Rabbit(100339079) ADAM metallopeptidase domain 15
  • domestic guinea pig(100736139) ADAM metallopeptidase domain 15
  • naked mole-rat(101712049) ADAM metallopeptidase domain 15

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADAM15 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ADAM15 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ADAM15,
Species
human
MISSION® esiRNA, targeting mouse Adam15,
Species
mouse