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Merck

ACMSD

aminocarboxymuconate semialdehyde decarboxylase

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(130013) Summary: The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004]
  • Mouse(266645) amino carboxymuconate semialdehyde decarboxylase
  • Rat(171385) aminocarboxymuconate semialdehyde decarboxylase
  • Zebrafish(557166) aminocarboxymuconate semialdehyde decarboxylase
  • chicken(424288) aminocarboxymuconate semialdehyde decarboxylase
  • domestic cat(101090201) aminocarboxymuconate semialdehyde decarboxylase
  • cow(515030) aminocarboxymuconate semialdehyde decarboxylase
  • dog(476125) aminocarboxymuconate semialdehyde decarboxylase
  • sheep(101107168) aminocarboxymuconate semialdehyde decarboxylase
  • domestic guinea pig(100735977) aminocarboxymuconate semialdehyde decarboxylase
  • naked mole-rat(101705072) aminocarboxymuconate semialdehyde decarboxylase

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ACMSD antibody produced in mouse, clone 3A9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-ACMSD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ACMSD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACMSD,
Species
human
MISSION® esiRNA, targeting mouse Acmsd,
Species
mouse