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ACIN1

apoptotic chromatin condensation inducer 1

Synonyms:
ACINUS, ACN, fSAP152
Species:
UniProtKB ID:
Gene ID:
  • Human(22985) Summary: Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(56215) apoptotic chromatin condensation inducer 1
  • Rat(305884) apoptotic chromatin condensation inducer 1
  • Horse(100055865) apoptotic chromatin condensation inducer 1
  • cow(534600) apoptotic chromatin condensation inducer 1
  • domestic cat(101092859) apoptotic chromatin condensation inducer 1
  • dog(480247) apoptotic chromatin condensation inducer 1
  • sheep(101122696) apoptotic chromatin condensation inducer 1
  • domestic guinea pig(100730104) apoptotic chromatin condensation inducer 1
  • naked mole-rat(101718648) apoptotic chromatin condensation inducer 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ACIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Acinus antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACIN1,
Species
human
MISSION® esiRNA, targeting mouse Acin1,
Species
mouse