ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
Synonyms:
ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11
Species:
Human ABCC5 (10057), Mouse Abcc5 (27416), Rat Abcc5 (116721), sheep ABCC5 (101123431), Domestic Rabbit ABCC5 (100351084), naked mole-rat Abcc5 (101718472), domestic guinea pig Abcc5 (100723026), Zebrafish abcc5 (336147), cow ABCC5 (511769), Horse ABCC5 (100066941) ...More
UniProtKB ID:
Gene ID:
- Human(10057) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008]
- Mouse(27416) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- Rat(116721) ATP-binding cassette, subfamily C (CFTR/MRP), member 5
- sheep(101123431) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- Domestic Rabbit(100351084) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- naked mole-rat(101718472) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- domestic guinea pig(100723026) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- Zebrafish(336147) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- cow(511769) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- Horse(100066941) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- domestic cat(101090542) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- chicken(424947) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- dog(478648) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MRP5 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-ABCC5 antibody produced in mouse, clone 1B12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-ABCC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-ABCC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Cell Lines
Product Number
Description
Species
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species