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AAK1

AP2 associated kinase 1

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(22848) Summary: Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(269774) AP2 associated kinase 1
  • Rat(500244) AP2 associated kinase 1
  • chicken(419512) AP2 associated kinase 1
  • dog(474625) AP2 associated kinase 1
  • domestic cat(101094013) AP2 associated kinase 1
  • cow(532546) AP2 associated kinase 1
  • Horse(100050738) AP2 associated kinase 1
  • naked mole-rat(101700174) AP2 associated kinase 1
  • domestic guinea pig(100727491) AP2 associated kinase 1
  • sheep(101107425) AP2 associated kinase 1
  • Domestic Rabbit(100356781) AP2 associated kinase 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-AAK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-AAK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-AAK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-AAK1 antibody produced in mouse, clone 4B10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Aak1,
Species
mouse
MISSION® esiRNA, targeting human AAK1 (2),
Species
human
MISSION® esiRNA, targeting mouse Aak1,
Species
mouse
MISSION® esiRNA, targeting human AAK1,
Species
human