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SML0934

Sigma-Aldrich

Enfuvirtide acetate salt

≥95% (HPLC)

Synonym(s):

T-20 acetate salt

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About This Item

Empirical Formula (Hill Notation):
C204H301N51O64 · xC2H4O2
CAS Number:
Molecular Weight:
4491.88 (free base basis)
UNSPSC Code:
51111800
NACRES:
NA.77

Assay

≥95% (HPLC)

form

powder

storage condition

desiccated
protect from light

color

white to off-white

shipped in

wet ice

storage temp.

−20°C

Amino Acid Sequence

Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu- Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu- Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu- Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2 acetate

General description

Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus. Enfuvirtide is catabolized with the help of proteolytic enzymes.

Biochem/physiol Actions

Enfuvirtide is an HIV fusion inhibitor used to patients with multi-drug resistant HIV. Enfuvirtide binds to gp41 preventing the creation of an entry pore for the HIV-1 virus.

Other Notes

Light sensitive

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Desk Encyclopedia of Microbiology (2010)

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