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Documentos clave

SAB3501039

Sigma-Aldrich

Anti-NRAS Antibody

rabbit polyclonal

Sinónimos:

Anti-ALPS4, Anti-CMNS, Anti-KRAS, Anti-N-ras, Anti-NCMS, Anti-NRAS1, Anti-NS6

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Nombre del producto

Anti-N-RAS antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 22 kDa

species reactivity

human, mouse, rat

concentration

1 mg/mL

technique(s)

ELISA: suitable
immunoblotting: suitable

NCBI accession no.

NP_002515

UniProt accession no.

P01111

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NRAS(4893)

Immunogen

Antibody was raised against a 15 amino acid peptide near the carboxy terminus of human N-RAS.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3501039.

Physical form

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
1204

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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

S Rodenhuis
Seminars in cancer biology, 3(4), 241-247 (1992-08-01)
Mutational activation of ras oncogenes is frequently encountered in human tumors. For unexplained reasons, K-ras mutations are predominantly found in pancreatic cancer, colorectal cancer and adeno-carcinoma of the lung, N-ras is predominantly found in a subset of acute leukemias and
S Malaney et al.
Journal of mammary gland biology and neoplasia, 6(1), 101-113 (2001-07-27)
The Ras superfamily of GTPases act as important regulatory switches to co-ordinate extracellular stimuli with activation of intracellular signaling pathways and appropriate biological responses. The Ras branch of this superfamily includes H-, K- and N-Ras, which are commonly mutated in
John T Swarthout et al.
The Journal of biological chemistry, 280(35), 31141-31148 (2005-07-08)
Covalent lipid modifications mediate the membrane attachment and biological activity of Ras proteins. All Ras isoforms are farnesylated and carboxyl-methylated at the terminal cysteine; H-Ras and N-Ras are further modified by palmitoylation. Yeast Ras is palmitoylated by the DHHC cysteine-rich
Annette Ehrhardt et al.
Experimental hematology, 30(10), 1089-1106 (2002-10-18)
Many members of the Ras superfamily of GTPases have been implicated in the regulation of hematopoietic cells, with roles in growth, survival, differentiation, cytokine production, chemotaxis, vesicle-trafficking, and phagocytosis. The well-known p21 Ras proteins H-Ras, N-Ras, K-Ras 4A, and K-Ras

Global Trade Item Number

Número de referencia del producto (SKU)GTIN
SAB3501039-100UG4061832498546

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